Significance of combining distal filter protection and a guiding catheter with temporary balloon occlusion for carotid artery stenting: clinical results and evaluation of debris capture

Ann Vasc Surg. 2012 Oct;26(7):929-36. doi: 10.1016/j.avsg.2012.04.022.

Abstract

Background: Carotid artery stenting (CAS) with distal filter protection allows for continuous cerebral perfusion. However, this procedure has been reported to be associated with a greater risk of debris migrating into the cerebral arteries. To improve the extent of debris capture, we used a guiding catheter with temporary balloon occlusion and temporary aspiration from the common carotid artery.

Methods: Eighty-one stenoses were treated with CAS using distal filter protection; simple distal filter protection (conventional group, n = 50) or distal filter protection with temporary proximal flow control and blood aspiration was performed using a 9-F guiding catheter with a temporary balloon occlusion positioned at the common carotid artery (proximal occlusion group, n = 31). Clinical outcomes, rates of capturing visible debris, and new ischemic signals on diffusion-weighted magnetic resonance imaging (DWI) were evaluated.

Results: Events involving procedure-related emboli causing neurological deficits occurred in 6.0% (3/50) and 3.2% (1/31) of patients in the conventional and proximal occlusion groups, respectively (P = 1.0). The rates of visible debris capture by using the distal filter were 64.0% (32/50) and 29.0% (9/31) in the convention and proximal occlusion groups, respectively, being significantly lower in the proximal occlusion group (P < 0.01). New ischemic signals on DWI were detected in 44.0% (22/50) and 12.9% (4/31) of cases in the conventional and proximal occlusion groups, respectively, being significantly lower in the proximal occlusion group (P < 0.01).

Conclusions: Combining distal filter protection and a guiding catheter with temporary balloon occlusion in CAS significantly reduced visible debris captured by the distal filter and occurrence of small postprocedural cerebral infarctions detected by DWI.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Angioplasty, Balloon / adverse effects
  • Angioplasty, Balloon / instrumentation*
  • Balloon Occlusion / instrumentation*
  • Carotid Stenosis / diagnostic imaging
  • Carotid Stenosis / therapy*
  • Catheters*
  • Cerebral Infarction / diagnosis
  • Cerebral Infarction / etiology
  • Cerebral Infarction / prevention & control*
  • Chi-Square Distribution
  • Diffusion Magnetic Resonance Imaging
  • Embolic Protection Devices*
  • Equipment Design
  • Female
  • Humans
  • Intracranial Embolism / diagnosis
  • Intracranial Embolism / etiology
  • Intracranial Embolism / prevention & control*
  • Magnetic Resonance Angiography / methods
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Prosthesis Design
  • Radiography
  • Stents*
  • Time Factors
  • Treatment Outcome