Implementation of an enhanced recovery programme following pancreaticoduodenectomy

HPB (Oxford). 2012 Oct;14(10):700-8. doi: 10.1111/j.1477-2574.2012.00521.x.

Abstract

Objectives: The aim of this prospective study was to investigate the implementation of an enhanced recovery after surgery (ERAS) programme following pancreaticoduodenectomy (PD).

Methods: Patients undergoing PD were managed according to an ERAS protocol. Outcome measures included postoperative mortality, morbidity, hospitalization and 30-day readmission rate. Key protocol targets were: nasogastric tube (NGT) removal [postoperative day (PoD) 1]; resumption of oral fluids (PoD 1); urinary catheter removal (PoD 3); high-dependency unit (HDU) discharge (PoD 3); tolerating diet (PoD 4); drain removal (PoD 5), and hospital discharge (PoD 6).

Results: Data were collected for 50 patients (24 male; median age 67 years). Rates of mortality, morbidity and readmission were 4%, 46% and 4%, respectively. The median length of postoperative hospitalization was 10 days. The proportions of patients achieving key targets were: 78% for NGT removal; 82% for resumption of oral fluids; 48% for urinary catheter removal; 82% for HDU discharge; 86% for tolerating diet; 84% for meeting mobility targets, and 72% for drain removal. One patient was discharged by PoD 6, eight patients by PoD 7, 15 patients by PoD 8 and 26 patients (52%) by PoD 10. Discharge was delayed in 16 patients for social or transport-related reasons.

Conclusions: The ERAS protocol was implemented safely. Achieving certain targets was challenging. Non-medical causes remain a significant factor in delayed discharge following PD.

MeSH terms

  • Aged
  • Analgesics / therapeutic use
  • Device Removal
  • Diet
  • Drainage / instrumentation
  • Female
  • Hospital Mortality
  • Humans
  • Intubation, Gastrointestinal / instrumentation
  • Length of Stay
  • Male
  • Pain Measurement
  • Pain, Postoperative / diagnosis
  • Pain, Postoperative / drug therapy
  • Pain, Postoperative / etiology
  • Pancreaticoduodenectomy* / adverse effects
  • Pancreaticoduodenectomy* / mortality
  • Patient Discharge
  • Patient Readmission
  • Pilot Projects
  • Program Evaluation
  • Prospective Studies
  • Recovery of Function
  • Severity of Illness Index
  • Time Factors
  • Treatment Outcome
  • Urinary Catheterization / instrumentation
  • Urinary Catheters

Substances

  • Analgesics