Multimodal treatment of hemorrhagic pituitary metastasis as first manifestation of renal cell carcinoma

World Neurosurg. 2013 May-Jun;79(5-6):798.E1-5. doi: 10.1016/j.wneu.2012.09.006. Epub 2012 Sep 16.

Abstract

Background: Metastatic tumors involving the pituitary gland are very rare, with only few cases reported so far in the literature.

Case description: We report a case of a man who presented with an extremely vascular hemorrhagic pituitary metastasis as the first manifestation of renal cell carcinoma. The patient was successfully treated with staged procedures, including preoperative tumor vasculature embolization followed by transsphenoidal tumor resection.

Conclusions: This is the first report describing multimodality treatment of a patient with pituitary metastasis of unknown origin requiring presurgical embolization before successful tumor removal.

Publication types

  • Case Reports

MeSH terms

  • Carcinoma, Renal Cell / blood supply
  • Carcinoma, Renal Cell / diagnosis
  • Carcinoma, Renal Cell / pathology
  • Carcinoma, Renal Cell / secondary*
  • Carcinoma, Renal Cell / therapy*
  • Cerebral Angiography
  • Cerebral Hemorrhage / diagnosis
  • Cerebral Hemorrhage / pathology
  • Cerebral Hemorrhage / therapy*
  • Diagnosis, Differential
  • Embolization, Therapeutic
  • Endoscopy
  • Humans
  • Hypophysectomy
  • Image Enhancement
  • Image Interpretation, Computer-Assisted
  • Kidney Neoplasms / blood supply
  • Kidney Neoplasms / diagnosis
  • Kidney Neoplasms / pathology
  • Kidney Neoplasms / therapy*
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Neoplasm, Residual / blood supply
  • Neoplasm, Residual / diagnosis
  • Neoplasm, Residual / pathology
  • Neoplasm, Residual / therapy
  • Nephrectomy
  • Pituitary Neoplasms / blood supply
  • Pituitary Neoplasms / diagnosis
  • Pituitary Neoplasms / pathology
  • Pituitary Neoplasms / secondary*
  • Pituitary Neoplasms / therapy*
  • Radiosurgery
  • Tomography, X-Ray Computed