[Hepatocellular adenomas and pregnancy]

Ned Tijdschr Geneeskd. 2012;156(38):A5102.
[Article in Dutch]

Abstract

Hepatocellular adenomas are benign liver tumours which are mostly seen in young women. When women with such tumours attempt to become pregnant, they require special attention because of the risks of hormone-induced growth and spontaneous rupture of the tumour, which are caused by increased levels of steroid hormones during pregnancy. We present three patients with hepatocellular adenomas who were either pregnant or wished to become pregnant. These cases describe the complexity of the situation. The size of the hepatocellular adenoma increased during pregnancy in patient A and contrarily remained stable in patient B. Patient C was advised to not get pregnant before an intervention because of the tumour's central location within the liver. We also describe the general clinical presentation and treatment of patients with a hepatocellular adenoma.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adenoma, Liver Cell / complications
  • Adenoma, Liver Cell / pathology*
  • Adenoma, Liver Cell / surgery
  • Adult
  • Contraceptives, Oral / adverse effects
  • Female
  • Humans
  • Liver Neoplasms / complications
  • Liver Neoplasms / pathology*
  • Liver Neoplasms / surgery
  • Pregnancy
  • Pregnancy Complications, Neoplastic / pathology*
  • Pregnancy Complications, Neoplastic / surgery
  • Pregnancy Outcome
  • Risk Assessment
  • Risk Factors
  • Rupture, Spontaneous / prevention & control
  • Watchful Waiting
  • Young Adult

Substances

  • Contraceptives, Oral