Development of a rapid multiplex PCR assay for identification of the three common Hemoglobin-Lepore variants (Boston-Washington, Baltimore, and Hollandia) and identification of a new Lepore variant

Am J Hematol. 2012 Oct;87(10):E74-5. doi: 10.1002/ajh.23304. Epub 2012 Aug 1.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Child
  • Child, Preschool
  • Chromosome Breakpoints
  • Chromosomes, Human, Pair 16 / genetics
  • Genotype
  • Hemoglobins, Abnormal / genetics*
  • Humans
  • Infant
  • Middle Aged
  • Polymerase Chain Reaction / methods*
  • Young Adult
  • alpha-Globins / genetics
  • beta-Globins / genetics
  • beta-Thalassemia / diagnosis
  • beta-Thalassemia / genetics*
  • delta-Globins / genetics
  • delta-Thalassemia / diagnosis
  • delta-Thalassemia / genetics

Substances

  • Hemoglobins, Abnormal
  • alpha-Globins
  • beta-Globins
  • delta-Globins
  • hemoglobin Lepore-ARUP
  • hemoglobin Lepore-Hollandia
  • hemoglobin Lepore Boston-Washington
  • hemoglobin Lepore Baltimore

Supplementary concepts

  • Delta-Beta Thalassemia