The enterococcal ABC transporter gene lsa(E) confers combined resistance to lincosamides, pleuromutilins and streptogramin A antibiotics in methicillin-susceptible and methicillin-resistant Staphylococcus aureus

J Antimicrob Chemother. 2013 Feb;68(2):473-5. doi: 10.1093/jac/dks398. Epub 2012 Oct 9.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • ATP-Binding Cassette Transporters / genetics
  • ATP-Binding Cassette Transporters / metabolism*
  • Amino Acid Sequence
  • Anti-Bacterial Agents / pharmacology*
  • Cluster Analysis
  • Diterpenes / pharmacology
  • Drug Resistance, Bacterial*
  • Enterococcus / genetics
  • Lincosamides / pharmacology*
  • Microbial Sensitivity Tests
  • Molecular Sequence Data
  • Phylogeny
  • Pleuromutilins
  • Polycyclic Compounds
  • Recombinant Proteins / genetics
  • Recombinant Proteins / metabolism
  • Sequence Homology, Amino Acid
  • Staphylococcus aureus / drug effects*
  • Staphylococcus aureus / genetics
  • Streptogramin A / pharmacology*

Substances

  • ATP-Binding Cassette Transporters
  • Anti-Bacterial Agents
  • Diterpenes
  • Lincosamides
  • Polycyclic Compounds
  • Recombinant Proteins
  • Streptogramin A