Small cell neuroendocrine carcinoma of the nasal cavity and paranasal sinuses: a rare case

J Laryngol Otol. 2012 Dec;126(12):1284-6. doi: 10.1017/S0022215112002435. Epub 2012 Oct 19.

Abstract

Objective: We report a rare case of small cell neuroendocrine carcinoma of the nasal cavity and paranasal sinuses with intracranial extension, and discuss the management of this rare tumour.

Results: Small cell neuroendocrine carcinoma involving the nasal cavity and paranasal sinuses with intracranial extension may be treated successfully with surgery alone, without development of local recurrence.

Conclusion: Small cell neuroendocrine carcinoma is a locally aggressive tumour with a high rate of recurrence. Early and aggressive surgical excision with or without radiotherapy or chemotherapy can improve a patient's outcome and prognosis. Regular follow up is needed to detect any local or distant recurrence.

Publication types

  • Case Reports

MeSH terms

  • Brain Neoplasms / pathology*
  • Carcinoma, Neuroendocrine / pathology
  • Carcinoma, Neuroendocrine / surgery*
  • Carcinoma, Small Cell / pathology
  • Carcinoma, Small Cell / surgery*
  • Humans
  • Male
  • Middle Aged
  • Nasal Cavity / pathology
  • Nasal Cavity / surgery*
  • Neoplasm Invasiveness / pathology
  • Neoplasm Recurrence, Local / pathology
  • Neoplasm Recurrence, Local / surgery
  • Nose Neoplasms / pathology
  • Nose Neoplasms / surgery
  • Paranasal Sinus Neoplasms / pathology
  • Paranasal Sinus Neoplasms / surgery*
  • Tomography, X-Ray Computed