Dual antiplatelet treatment in patients candidates for abdominal surgery

Ann Ital Chir. 2013 May-Jun;84(3):291-4.

Abstract

With the increasing diffusion of percutaneous interventions (PCI), surgeons are often faced with the problem of operating on patients under dual antiplatelet treatment. Replacing dual antiplatelet regiment with low molecular weight heparin may expose to the abrupt thrombosis of coronary stent and massive myocardial infarction. The purpose of this study was to test the hypothesis that abdominal operations can be safely performed under dual antiplatelet treatment. Eleven patients underwent 5 colectomies, 3 nefrectomies, 2 gastrectomies and 1 hysterectomy under aspirin and plavix without any significant perioperative hemorrhage. These preliminary results show that abdominal operations can be safely performed under dual antiplatelet regimen.

Key words: Abdominal surgery, Dual antiplatelet treatment.

MeSH terms

  • Abdomen / surgery*
  • Aged
  • Drug Therapy, Combination
  • Female
  • Humans
  • Male
  • Middle Aged
  • Platelet Aggregation Inhibitors / therapeutic use*
  • Retrospective Studies
  • Risk Factors
  • Surgical Procedures, Operative

Substances

  • Platelet Aggregation Inhibitors