A dicentric variant of chromosome 6: characterization by use of in situ hybridisation with the biotinylated probe p308

D F Callen; H J Eyre; M L Ringenbergs

doi:10.1111/j.1399-0004.1990.tb03483.x

A dicentric variant of chromosome 6: characterization by use of in situ hybridisation with the biotinylated probe p308

Clin Genet. 1990 Feb;37(2):81-3. doi: 10.1111/j.1399-0004.1990.tb03483.x.

Authors

D F Callen¹, H J Eyre, M L Ringenbergs

Affiliation

¹ Cytogenetics Unit, Aldelaide Children's Hospital, South Australia.

PMID: 2311270
DOI: 10.1111/j.1399-0004.1990.tb03483.x

Abstract

An unusual variant of chromosome 6 was shown to be a dic(6) by use of the chromosome specific alphoid probe, p308. The use of biotinylated repeat probes provides a rapid procedure for the resolution of some cytogenetic abnormalities.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Centromere / ultrastructure*
Chromosome Banding
Chromosomes / ultrastructure*
Chromosomes, Human, Pair 6 / ultrastructure*
DNA Probes*
DNA, Satellite / genetics
Extrachromosomal Inheritance / genetics*
Genetic Variation / genetics*
Humans
Nucleic Acid Hybridization / physiology
Puberty, Delayed / genetics*
Repetitive Sequences, Nucleic Acid / physiology

Substances

DNA Probes
DNA, Satellite