Direct binding of Grb2 has an important role in the development of myeloproliferative disease induced by ETV6/FLT3

Leukemia. 2013 Jun;27(6):1433-6. doi: 10.1038/leu.2012.333. Epub 2012 Nov 20.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • ETS Translocation Variant 6 Protein
  • GRB2 Adaptor Protein / metabolism*
  • Humans
  • Myeloproliferative Disorders / metabolism*
  • Protein Binding
  • Proto-Oncogene Proteins c-ets / physiology*
  • Repressor Proteins / physiology*
  • fms-Like Tyrosine Kinase 3 / physiology*

Substances

  • GRB2 Adaptor Protein
  • Proto-Oncogene Proteins c-ets
  • Repressor Proteins
  • FLT3 protein, human
  • fms-Like Tyrosine Kinase 3