Abstract
Ovarian cancer is the most lethal of the gynaecological malignancies because this «silent killer» is almost always diagnosed at an advanced stage. Precursor lesions have at least been discovered. This review will describe in details specific features of tubal and ovarian preinvasive lesions and the old and novel techniques that could be used for early detection of ovarian cancer.
Copyright © 2012 Elsevier Masson SAS. All rights reserved.
MeSH terms
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Biomarkers, Tumor / analysis
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Biomarkers, Tumor / physiology
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Carcinoma / diagnosis*
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Carcinoma / epidemiology
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Carcinoma / genetics
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Carcinoma in Situ / diagnosis
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Carcinoma in Situ / epidemiology
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Carcinoma in Situ / genetics
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Early Detection of Cancer / methods
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Early Detection of Cancer / trends*
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Female
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Humans
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Models, Biological
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Ovarian Neoplasms / diagnosis*
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Ovarian Neoplasms / epidemiology
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Ovarian Neoplasms / genetics
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Precancerous Conditions / diagnosis
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Precancerous Conditions / epidemiology
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Precancerous Conditions / genetics
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Ultrasonography
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Vagina / diagnostic imaging