An algebraic iterative reconstruction technique for differential X-ray phase-contrast computed tomography

Z Med Phys. 2013 Sep;23(3):186-93. doi: 10.1016/j.zemedi.2012.11.002. Epub 2012 Nov 29.

Abstract

Iterative reconstruction has a wide spectrum of proven advantages in the field of conventional X-ray absorption-based computed tomography (CT). In this paper, we report on an algebraic iterative reconstruction technique for grating-based differential phase-contrast CT (DPC-CT). Due to the differential nature of DPC-CT projections, a differential operator and a smoothing operator are added to the iterative reconstruction, compared to the one commonly used for absorption-based CT data. This work comprises a numerical study of the algorithm and its experimental verification using a dataset measured at a two-grating interferometer setup. Since the algorithm is easy to implement and allows for the extension to various regularization possibilities, we expect a significant impact of the method for improving future medical and industrial DPC-CT applications.

Keywords: Computertomographie; Differential phase-contrast imaging; Differentielle Phasenkontrast-Bildgebung; Iterative Algebraische Rekonstruktionstechnik; Rekonstruktionsalgorithmus; algebraic itrative reconstruction; computed tomography; reconstruction algorithm.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms*
  • Animals
  • Humans
  • Phantoms, Imaging
  • Radiographic Image Enhancement / methods*
  • Radiographic Image Interpretation, Computer-Assisted / methods*
  • Refractometry / instrumentation
  • Refractometry / methods*
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Tomography, X-Ray Computed / instrumentation
  • Tomography, X-Ray Computed / methods*
  • X-Ray Diffraction / instrumentation
  • X-Ray Diffraction / methods*