Abstract
We have demonstrated that curcumin is an amyloid-specific dye in E. coli. Curcumin binds to curliated whole cells and to isolated curli amyloid fibers. Similar to Congo red, curcumin exhibits a red-shift in absorbance and a significant increase in fluorescence upon binding to isolated curli.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Amyloid / chemistry*
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Amyloid / metabolism
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Benzenesulfonates / chemistry
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Biofilms
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Coloring Agents / chemistry*
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Congo Red / chemistry
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Curcumin / chemistry*
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Escherichia coli / physiology*
Substances
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Amyloid
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Benzenesulfonates
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Coloring Agents
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Congo Red
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C.I. Fluorescent Brightening Agent 28
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Curcumin