Eosinophilic fasciitis characterized by symmetrical limbs' edema, myalgia, erythema, and progressive cutaneous and subcutaneous induration. Peripheral eosinophilia and hypergammaglobulinaemia are the most characteristic features of the disease. Histopathological examination shows fibrosis of fascia and deep layers of subcutaneous tissue with inflammatory infiltrates of eosinophiles, lymphocytes, histiocytes, and plasmocytes. The involvement of the organs occurs rarely in the course of the disease. The clinical case of eosinophilic fasciitis in a 78-year-old female patient was described.