A treatment strategy for early thrombosed Stanford type A acute aortic dissection

Gen Thorac Cardiovasc Surg. 2013 Feb;61(2):84-8. doi: 10.1007/s11748-012-0194-0. Epub 2013 Jan 5.

Abstract

Objective: Early thrombosed aortic dissection is a form of aortic dissection and includes the condition called aortic intramural hematoma. It was generally considered as surgical emergency. However, the optimal treatment strategy for acute type A intramural hematoma is becoming controversial after recent studies indicated more benign clinical course for this disease. We evaluated our strategy that integrated medical therapy, serial imaging, and timed surgery.

Methods: We reviewed 34 consecutive patients who were admitted to our hospital for early thrombosed Stanford type A acute aortic dissection from 2006 to 2011. Medical therapy or timed surgery was offered on the basis of radiological findings. Emergency or urgent surgery was not considered for a hemodynamically stable patient unless the ascending aortic diameter was ≧50 mm or the thickness of the thrombosed false lumen was ≧10 mm. Follow-up computed tomography was performed to detect a potential progression to aortic dissection.

Results: During the average follow-up period of 24.3 months, there was no aortic dissection-related mortality. And aortic dissection-related event was not recorded in patients who had surgical repair; however, in patients who did not have surgery, 3 (8.8 %) surgical conversions were recorded due to aortic dissection progression during the follow-up period. Twenty-one patients (61.8 %) ultimately had surgical repair, and 13 patients (38.2 %) had complete medical therapy. The overall survival rate at 3 years was 86.5 %.

Conclusions: Our strategy for the treatment of early thrombosed Stanford type A acute aortic dissection is reasonable, and the mid-term results were acceptable.

MeSH terms

  • Aged
  • Aortic Aneurysm / diagnostic imaging
  • Aortic Aneurysm / mortality
  • Aortic Aneurysm / therapy*
  • Aortic Dissection / diagnostic imaging
  • Aortic Dissection / mortality
  • Aortic Dissection / therapy*
  • Disease Progression
  • Emergency Treatment / methods*
  • Female
  • Hematoma / diagnostic imaging
  • Hematoma / mortality
  • Hematoma / therapy*
  • Humans
  • Male
  • Survival Rate
  • Thrombosis / diagnostic imaging
  • Thrombosis / mortality
  • Thrombosis / therapy*
  • Tomography, X-Ray Computed