A turn-on fluorescent sensor for the discrimination of cystein from homocystein and glutathione

Chem Commun (Camb). 2013 Feb 14;49(13):1294-6. doi: 10.1039/c2cc38429a. Epub 2013 Jan 8.

Abstract

We report a turn-on fluorescent sensor based on nitrothiophenolate boron dipyrromethene (BODIPY) derivatives for the discrimination of cystein (Cys) from homocystein (Hcy) and glutathione (GSH). The sensor was applied for detection of Cys in living cells.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cysteine / analysis*
  • Cysteine / chemistry*
  • Glutathione / analysis*
  • Glutathione / chemistry*
  • HeLa Cells
  • Homocysteine / analysis*
  • Homocysteine / chemistry*
  • Humans
  • Spectrometry, Fluorescence
  • Sulfhydryl Compounds / chemistry

Substances

  • Sulfhydryl Compounds
  • Homocysteine
  • Glutathione
  • Cysteine