Pre-operative assessment of living renal transplant donors with state-of-the-art imaging modalities: computed tomography angiography versus magnetic resonance angiography in 118 patients

World J Urol. 2013 Aug;31(4):983-90. doi: 10.1007/s00345-012-1022-y. Epub 2013 Jan 8.

Abstract

Purpose: To compare current technology multislice computed tomography angiography (CTA) with magnetic resonance angiography (MRA) in the pre-operative evaluation of vascular anatomy of living renal transplant donors.

Methods and materials: Two hundred and thirty-six kidneys were included in the CTA and MRA analysis. Renal vasculature was evaluated independently by two readers in each modality with a delay of 4 weeks between reading sessions. Surgical correlation on the operated side was available in all patients. The reference standard was defined by surgical correlation and consensus reading of both modalities.

Results: Detection rate of CTA for arteries was 99.1 and 95.0 % for reader 1 and reader 2, respectively. Detection rate of MRA for arteries was 95.0/94.3 %. Most of the undetected arteries were ≤ 1 mm diameter (reader 1: 2 of 3 in CTA and 9 of 16 in MRA; reader 2: 11 of 16 in CTA, and 8 of 18 in MRA). Detection rates for arteries ≥ 2 mm for reader 1/reader 2 were 99.7/98.7 % in CTA and 99.1/97.8 % in MRA, respectively. Detection rates for veins were 99.6/97.4 % in CTA and 97.8/96.9 % in MRA, respectively. Both readers misdiagnosed between 0 and 1 non-present arteries and between 2 and 3 non-present veins in both modalities.

Conclusions: Modern multislice CT and MRI scanners allow highly accurate evaluation of the vascular anatomy, especially for vessels of ≥ 2 mm diameter. CTA may provide slightly better depiction of very small arteries; however, this may be reader-dependent. Additional factors affecting the choice of imaging modality should include local availability, cost, and the desire to avoid ionizing radiation in healthy transplant donors.

Publication types

  • Comparative Study

MeSH terms

  • Angiography* / methods
  • Arterial Occlusive Diseases / diagnosis
  • Arterial Occlusive Diseases / diagnostic imaging
  • Arterial Occlusive Diseases / pathology
  • Contrast Media / adverse effects
  • Humans
  • Image Processing, Computer-Assisted / methods
  • Kidney / blood supply*
  • Kidney / diagnostic imaging
  • Kidney / pathology
  • Kidney Transplantation*
  • Living Donors*
  • Magnetic Resonance Angiography*
  • Observer Variation
  • Preoperative Care
  • Renal Artery* / diagnostic imaging
  • Renal Artery* / pathology
  • Retrospective Studies
  • Tomography, X-Ray Computed

Substances

  • Contrast Media