Abstract
The increase in density of information available in relation to patients and research participants, in particular in the context of genetic diagnostics and analysis, results in an increased potential for uncovering details which were unexpected but are of particular significance for the patient. Deciding how this information is dealt with and who is entitled to receive this information, is a medicolegal and ethical balancing act. Incidental findings and the challenges posed by the advent of personalised medicine are but two areas which increasingly impact medical disciplines that do not conventionally work directly with patients. Both areas raise questions of what is legally required and morally necessary. The authors briefly sketch these two areas and the medicolegal and ethical implications for diagnostics and research in pathology.
MeSH terms
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Adult
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Antineoplastic Agents / toxicity
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Biomedical Research / ethics*
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Biomedical Research / legislation & jurisprudence*
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Child
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Confidentiality / ethics*
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Confidentiality / legislation & jurisprudence*
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Education, Medical, Continuing / ethics
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Education, Medical, Continuing / legislation & jurisprudence
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Ethics, Medical*
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Female
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Genetic Privacy / ethics
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Genetic Privacy / legislation & jurisprudence
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Genetic Testing / ethics
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Genetic Testing / legislation & jurisprudence
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Germany
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Humans
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Incidental Findings*
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Male
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Malpractice / legislation & jurisprudence
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Morals
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Pathology / ethics*
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Pathology / legislation & jurisprudence*
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Pathology, Molecular / ethics*
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Pathology, Molecular / legislation & jurisprudence*
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Patient Advocacy / ethics
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Patient Advocacy / legislation & jurisprudence
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Patient Education as Topic / ethics
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Patient Education as Topic / legislation & jurisprudence
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Personal Autonomy
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Pharmacogenetics
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Precision Medicine / ethics
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Risk Assessment
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Truth Disclosure / ethics