Abstract
We describe a case of hemophagocytic lymphohistiocytosis related to visceral leishmaniasis in late adulthood. Because clinical features of visceral leishmaniasis can mimic those of hemophagocytic lymphohistiocytosis, diagnosing leishmaniasis as the underlying etiology can be quite challenging. In our case, treatment with amphotericin B resulted in a dramatic resolution of clinical abnormalities.
MeSH terms
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Aged
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Amphotericin B / therapeutic use
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Anti-Inflammatory Agents / therapeutic use
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Antiprotozoal Agents / therapeutic use
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Dexamethasone / therapeutic use
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Disseminated Intravascular Coagulation / complications
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Disseminated Intravascular Coagulation / pathology
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Hepatomegaly / etiology
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Hepatomegaly / pathology
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Humans
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Leishmaniasis, Visceral / complications*
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Leishmaniasis, Visceral / drug therapy
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Leishmaniasis, Visceral / pathology
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Lymphohistiocytosis, Hemophagocytic / complications*
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Lymphohistiocytosis, Hemophagocytic / pathology
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Male
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Splenomegaly / etiology
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Splenomegaly / pathology
Substances
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Anti-Inflammatory Agents
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Antiprotozoal Agents
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Dexamethasone
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Amphotericin B