Combined statistical analysis method assessing fast versus slow movement training in a patient with cerebellar stroke: a single-case study

Phys Ther. 2013 May;93(5):649-60. doi: 10.2522/ptj.20120121. Epub 2013 Jan 17.

Abstract

Background: Gold standards of data analysis for single-case research do not currently exist.

Objective: The purpose of this study was to determine whether a combined statistical analysis method is more effective in assessing movement training effects in a patient with cerebellar stroke.

Design: A crossover single-case research design was conducted.

Methods: The patient was a 69-year-old man with a chronic cerebellar infarct who received two 5-week phases of finger tracking training at different movement rates. Changes were measured with the Box and Block Test, the Jebsen-Taylor test, the finger extension force test, and the corticospinal excitability test. Both visual analysis and statistical tests (including split-middle line method, t test, confidence interval, and effect size) were used to assess potential intervention effects.

Results: The results of the t tests were highly consistent with the confidence interval tests, but less consistent with the split-middle line method. Most results produced medium to large effect sizes.

Limitations: The possibility of an incomplete washout effect was a confounding factor in the current analyses.

Conclusions: The combined statistical analysis method may assist researchers in assessing intervention effects in single-case stroke rehabilitation studies.

Publication types

  • Case Reports
  • Comparative Study
  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Brain Infarction / physiopathology
  • Brain Infarction / rehabilitation*
  • Cerebellar Diseases / physiopathology
  • Cerebellar Diseases / rehabilitation*
  • Electromyography
  • Exercise Movement Techniques / methods*
  • Humans
  • Infarction / rehabilitation*
  • Male
  • Palatine Tonsil / blood supply*
  • Pyramidal Tracts / physiopathology
  • Research Design
  • Statistics as Topic / methods*
  • Stroke / physiopathology
  • Stroke Rehabilitation*