A rare case of adult hepatoblastoma with neuroendocrine differentiation misdiagnosed as neuroendocrine tumor

Int J Clin Exp Pathol. 2013;6(2):308-13. Epub 2013 Jan 15.

Abstract

Hepatoblastoma is the most common malignant liver tumor between the age of 6 months and 3 years, but it is extremely rare in adults. Only Forty-five cases of adult hepatoblastoma were reported up to now in the world. Hepatoblastoma exhibits a wide range of epithelial and mesenchymal lines differentiation, but neuroendocrine differentiation of this tumor has rare been reported in the literature. Here, we reported a case of primary giant hepatoblastoma (about 11.4*7.9*15.3 cm) with neuroendocrine differentiation of a 32-year-old woman, which was misdiagnosed as neuroendocrine tumor.

Keywords: Hepatoblastoma; immunohistochemistry; neuroendocrine tumour (NET); squamous corpuscles.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Carcinoma, Neuroendocrine / diagnosis*
  • Carcinoma, Neuroendocrine / pathology
  • Cell Differentiation
  • Diagnosis, Differential
  • Diagnostic Errors*
  • Female
  • Hepatoblastoma / diagnosis*
  • Hepatoblastoma / pathology
  • Humans
  • Liver Neoplasms / diagnosis*
  • Liver Neoplasms / pathology
  • Magnetic Resonance Imaging