Adjustment of antiretroviral regimen may lead to HBV reactivation even in patients with past HBV infection serological profile

Sophie Seang; Vincent Thibault; Marc Antoine Valantin; Christine Katlama

doi:10.1007/s10156-013-0560-6

Adjustment of antiretroviral regimen may lead to HBV reactivation even in patients with past HBV infection serological profile

J Infect Chemother. 2013 Oct;19(5):987-9. doi: 10.1007/s10156-013-0560-6. Epub 2013 Feb 5.

Authors

Sophie Seang¹, Vincent Thibault, Marc Antoine Valantin, Christine Katlama

Affiliation

¹ INSERM UMR-S 943 and University Pierre and Marie Curie (UPMC) Paris VI, Paris, France, sophie.seang@yahoo.fr.

PMID: 23380971
DOI: 10.1007/s10156-013-0560-6

Abstract

We report a reactivation of hepatitis B virus (HBV) in an human immunodeficiency virus (HIV) patient despite a serological profile of past HBV infection with anti-HBs and anti-HBc antibodies, following the interruption of tenofovir/emtricitabine. In HBV-HIV co-infected patients, close monitoring of HBV viral load and serological markers is required for antiretroviral management, particularly after interruption of drugs active for HBV.

Publication types

Case Reports

MeSH terms

Anti-Retroviral Agents / adverse effects*
Anti-Retroviral Agents / therapeutic use
Antibodies, Viral / blood
HIV Infections / drug therapy*
HIV Infections / virology*
HIV-1 / isolation & purification*
Hepatitis B / blood
Hepatitis B / immunology
Hepatitis B / virology*
Hepatitis B virus / physiology*
Humans
Male
Middle Aged
Viral Load
Virus Activation / drug effects

Substances

Anti-Retroviral Agents
Antibodies, Viral