[Subarachnoidal hemorrhage and multiple vascular cerebral abnormalities in β-thalassemia major]

Rev Neurol (Paris). 2013 Mar;169(3):266-8. doi: 10.1016/j.neurol.2012.09.015. Epub 2013 Feb 6.
[Article in French]

Abstract

β-thalassemia is a genetic hemoglobinopathy, which can cause hypercoagulability, vessel wall damages and thromboembolic events. Spontaneous subarachnoidal hemorrhages are not commonly described in this affection. We report subarachnoidal hemorrhage, observed during the post-partum period in a 27-year-old woman suffering from β-thalassemia major. Brain MRI revealed complex vascular abnormalities: intracranial carotid occlusion, carotid micro-aneurisms, abnormally developed deep perforators and cortical arteries.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Cerebral Angiography
  • Cerebrovascular Disorders / complications*
  • Cerebrovascular Disorders / diagnosis
  • Female
  • Humans
  • Puerperal Disorders / diagnosis
  • Puerperal Disorders / etiology
  • Subarachnoid Hemorrhage / complications*
  • Subarachnoid Hemorrhage / diagnosis
  • beta-Thalassemia / complications*
  • beta-Thalassemia / diagnosis