Effectiveness of seasonal 2012/13 vaccine in preventing laboratory-confirmed influenza infection in primary care in the United Kingdom: mid-season analysis 2012/13

Euro Surveill. 2013 Jan 31;18(5):20393. doi: 10.2807/ese.18.05.20393-en.

Abstract

The early experience of the United Kingdom (UK) is that influenza B has dominated the influenza 2012/13 season. Overall trivalent influenza vaccine (TIV) adjusted vaccine effectiveness (VE) against all laboratory-confirmed influenza in primary care was 51% (95% confidence interval (CI): 27% to 68%); TIV adjusted VE against influenza A alone or influenza B alone was 49% (95% CI: -2% to 75%) and 52% (95% CI: 23% to 70%) respectively. Vaccination remains the best protection against influenza.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Aged
  • Aged, 80 and over
  • Case-Control Studies
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Influenza A virus / genetics
  • Influenza A virus / immunology
  • Influenza A virus / isolation & purification*
  • Influenza B virus / genetics
  • Influenza B virus / immunology
  • Influenza B virus / isolation & purification*
  • Influenza Vaccines / administration & dosage*
  • Influenza Vaccines / immunology
  • Influenza, Human / diagnosis
  • Influenza, Human / epidemiology
  • Influenza, Human / prevention & control*
  • Influenza, Human / virology
  • Logistic Models
  • Male
  • Middle Aged
  • Odds Ratio
  • Primary Health Care
  • Real-Time Polymerase Chain Reaction
  • Seasons*
  • Sentinel Surveillance
  • Surveys and Questionnaires
  • Treatment Outcome
  • United Kingdom / epidemiology
  • Vaccination / statistics & numerical data
  • Young Adult

Substances

  • Influenza Vaccines