[Diagnosis and management of lung cancer during pregnancy]

Rev Mal Respir. 2013 Feb;30(2):125-36. doi: 10.1016/j.rmr.2012.11.003. Epub 2012 Dec 31.
[Article in French]

Abstract

The incidence of lung cancer during pregnancy is very low, but it is becoming more frequent in industrialized countries both because of the increase in smoking in young women and because women are becoming pregnant later in life. Usually, the cancer has a poor prognosis due to the presence of metastatic disease at the time of diagnosis. Diagnosis and management are delicate, and should deal with the gestational age, the maternal prognosis, the fetal toxicity of treatments, but also with the worsening of maternal prognosis and the risk of neoplastic cells being transmitted to the fetus in case of delayed treatment. Psychological and ethical considerations complicate the decision process. We present a review of the epidemiology, clinical characteristics, management, and prognosis concerning lung cancer during pregnancy. Finally, it is important to remember that young women with lung cancer should be advised to use a reliable form of contraception.

Publication types

  • Review

MeSH terms

  • Abnormalities, Drug-Induced / prevention & control
  • Abnormalities, Radiation-Induced / prevention & control
  • Abortion, Therapeutic
  • Adult
  • Antineoplastic Agents / adverse effects
  • Antineoplastic Agents / therapeutic use
  • Breast Feeding
  • Contraception
  • Contraindications
  • Diagnostic Imaging / adverse effects
  • Diagnostic Imaging / methods
  • Disease Management
  • Female
  • Fetus / drug effects
  • Fetus / radiation effects
  • Humans
  • Incidence
  • Infant, Newborn
  • Lung Neoplasms / diagnosis*
  • Lung Neoplasms / epidemiology
  • Lung Neoplasms / therapy*
  • Maternal Age
  • Maternal-Fetal Exchange
  • Neoplasms / congenital
  • Neoplastic Cells, Circulating
  • Pregnancy
  • Pregnancy Complications, Neoplastic / diagnosis*
  • Pregnancy Complications, Neoplastic / epidemiology
  • Pregnancy Complications, Neoplastic / therapy*
  • Pregnancy Outcome
  • Prognosis
  • Radiotherapy / adverse effects
  • Risk Factors
  • Smoking / adverse effects
  • Smoking / epidemiology

Substances

  • Antineoplastic Agents