Abstract
A new strategy for iminium ion isomerization was applied to the direct, redox-neutral α-alkynylation of amines. Cu(II) 2-ethylhexanoate was identified as the optimal catalyst for this three-component coupling reaction of secondary amines, aldehydes and alkynes.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Amines / chemistry*
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Carboxylic Acids / chemistry*
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Catalysis
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Copper / chemistry*
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Isomerism
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Microwaves
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Oxidation-Reduction
Substances
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Amines
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Carboxylic Acids
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Copper