Management of aortic aneurysms in patients with connective tissue disease

J Cardiovasc Surg (Torino). 2013 Feb;54(1 Suppl 1):125-34.

Abstract

Acute dissection and rupture of aortic aneurysms comprise for 1-2% of all deaths in developed countries. Dilation of the aorta is caused by several different mechanisms including inherited disorders of connective tissue. Recent reports estimate that 20% of patients presenting with thoracic aortic disease do have an underlying genetic basis of disease.

Publication types

  • Review

MeSH terms

  • Adult
  • Aged
  • Aortic Aneurysm / diagnostic imaging
  • Aortic Aneurysm / genetics
  • Aortic Aneurysm / surgery*
  • Aortography / methods
  • Blood Vessel Prosthesis Implantation* / adverse effects
  • Connective Tissue Diseases / complications*
  • Connective Tissue Diseases / diagnosis
  • Connective Tissue Diseases / genetics
  • Ehlers-Danlos Syndrome / complications
  • Endovascular Procedures* / adverse effects
  • Female
  • Genetic Predisposition to Disease
  • Humans
  • Loeys-Dietz Syndrome / complications
  • Male
  • Marfan Syndrome / complications
  • Middle Aged
  • Patient Selection
  • Phenotype
  • Pregnancy
  • Risk Assessment
  • Risk Factors
  • Tomography, X-Ray Computed
  • Treatment Outcome