Abstract
We examined the relationship between plasma adipokine concentrations and ultrasound measures of vascular health in 100 HIV-infected adults on antiretroviral therapy. Leptin was positively correlated with flow-mediated dilation of the brachial artery and negatively with carotid intima-media thickness. These relationships were independent of traditional risk factors and trunk fat in women but not men. Neither adiponectin nor resistin was associated with either measure of vascular health.
Publication types
-
Research Support, N.I.H., Extramural
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Absorptiometry, Photon
-
Adipokines / blood*
-
Adult
-
Anti-HIV Agents / therapeutic use
-
Body Mass Index
-
Brachial Artery / diagnostic imaging
-
Carotid Arteries / diagnostic imaging
-
Carotid Artery Diseases / diagnostic imaging*
-
Enzyme-Linked Immunosorbent Assay
-
Female
-
HIV Infections / blood*
-
HIV Infections / drug therapy
-
Humans
-
Leptin / blood
-
Male
-
Middle Aged
-
Obesity / blood*
-
Resistin / blood
-
Risk Factors
-
Ultrasonography
Substances
-
Adipokines
-
Anti-HIV Agents
-
Leptin
-
Resistin