Multiple atypical recurrent meningiomas 13 years after radiotherapy for unilateral retinoblastoma: case report and review of the literature

Neurol Neurochir Pol. 2013 Jan-Feb;47(1):80-5. doi: 10.5114/ninp.2013.32932.

Abstract

Radiotherapy is an important treatment modality for intracranial malignancies. Improved survival rates were achieved via a combination of surgery, chemotherapy and radiotherapy. On the other hand, improved survival rates made long-term complications of radiotherapy more apparent. Secondary neoplasms due to cranial irradiation are encountered more commonly in neurosurgical practice. Radiation-induced meningiomas are recognized as a common late complication of radiotherapy. However, radiation-induced meningiomas after radiotherapy for retinoblastoma have been reported rarely. Herein we report a patient who harboured multiple meningiomas 13 years after radiotherapy for unilateral retinoblastoma, which were recurrent despite surgical removal and chemotherapy.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Combined Modality Therapy
  • Humans
  • Male
  • Meningioma / pathology
  • Meningioma / surgery*
  • Neoplasm Recurrence, Local / pathology
  • Neoplasm Recurrence, Local / surgery*
  • Neoplasms, Radiation-Induced / pathology
  • Neoplasms, Radiation-Induced / surgery*
  • Retinal Neoplasms / radiotherapy*
  • Retinoblastoma / radiotherapy*
  • Treatment Outcome

Supplementary concepts

  • Radiation induced meningioma