Sodium valproate induced increased frequency of micturition and enuresis

Indian J Pharmacol. 2013 Jan-Feb;45(1):87-8. doi: 10.4103/0253-7613.106443.

Abstract

Sodium valproate is a commonly used antiepileptic drug (AED) for control of a broad range of seizures. Adverse drug reactions (ADR) due to sodium valproate range from sedation to nausea, vomiting, weight gain, idiosyncratic adverse effects like hepatotoxicity and life threatening conditions like pancreatitis. We present a case of sodium valproate induced enuresis in child. This ADR of valproate is an underreported ADR and requires special attention of pediatricians as it can interfere with the further treatment of the disease.

Keywords: Adverse drug reactions; enuresis; valproate.

Publication types

  • Case Reports

MeSH terms

  • Anticonvulsants / adverse effects*
  • Child, Preschool
  • Enuresis / chemically induced*
  • Humans
  • Male
  • Seizures / drug therapy*
  • Urination / drug effects
  • Valproic Acid / adverse effects*

Substances

  • Anticonvulsants
  • Valproic Acid