Abstract
GeneXpert CT/NG was evaluated with 372 characterized bacterial strains. Sensitivity of 10 genome copies/reaction was obtained for both agents. Four Neisseria mucosa and two Neisseria subflava isolates were positive for one of two gonococcal targets; however, the assay flagged all as negative. The assay was analytically highly sensitive and specific.
Publication types
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Evaluation Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Bacteriological Techniques / methods*
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Chlamydia trachomatis / classification
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Chlamydia trachomatis / genetics
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Chlamydia trachomatis / isolation & purification*
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Gonorrhea / diagnosis*
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Gonorrhea / microbiology
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Humans
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Lymphogranuloma Venereum / diagnosis*
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Lymphogranuloma Venereum / microbiology
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Male
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Molecular Diagnostic Techniques / methods*
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Neisseria gonorrhoeae / classification
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Neisseria gonorrhoeae / genetics
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Neisseria gonorrhoeae / isolation & purification*
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Point-of-Care Systems*
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Sensitivity and Specificity