Oncocytic Schneiderian papillomas: Clinical behavior and outcomes of the endoscopic endonasal approach in 33 cases

Head Neck. 2014 May;36(5):624-30. doi: 10.1002/hed.23341. Epub 2013 Jul 2.

Abstract

Background: The purpose of this study was to evaluate the clinical behavior of oncocytic Schneiderian papillomas in relation to the rate of malignant transformation and recurrences and to report the long-term results of the endoscopic endonasal treatment.

Methods: A retrospective analysis was carried out on patients with oncocytic papilloma, endoscopically managed over the past 20 years, at 2 university centers following a uniform policy.

Results: Thirty-three patients were treated between November 1991 and December 2010. The mean follow-up period was 62 months. We observed 2 cases of persistence (6%) at the maxillary sinus level. Both of these patients underwent endoscopic surgical revision. Squamous cell carcinoma (SCC) was observed in 1 patient (3%).

Conclusion: The endonasal endoscopic technique proved to be a safe and effective approach for the treatment of oncocytic papillomas. An oncocytic papilloma is not to be considered a negative prognostic factor in terms of malignant transformation or recurrence.

Keywords: endoscopic endonasal approach; inverted papilloma; oncocytic Schneiderian papilloma; sinonasal benign tumors; skull base.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Biopsy, Needle
  • Cell Transformation, Neoplastic
  • Endoscopy / methods*
  • Female
  • Follow-Up Studies
  • Humans
  • Immunohistochemistry
  • Italy
  • Magnetic Resonance Imaging / methods
  • Male
  • Middle Aged
  • Nasal Cavity / surgery
  • Nasal Mucosa / pathology
  • Neoplasm Invasiveness / pathology
  • Neoplasm Recurrence, Local / pathology*
  • Neoplasm Recurrence, Local / surgery
  • Neoplasm Staging
  • Nose Neoplasms / mortality
  • Nose Neoplasms / pathology*
  • Nose Neoplasms / surgery*
  • Oxyphil Cells / pathology
  • Papilloma, Inverted / pathology*
  • Papilloma, Inverted / surgery*
  • Paranasal Sinus Neoplasms / pathology
  • Paranasal Sinus Neoplasms / surgery
  • Retrospective Studies
  • Risk Assessment
  • Sampling Studies
  • Survival Rate
  • Tomography, X-Ray Computed
  • Treatment Outcome