Sequence-specific backbone ¹H, ¹³C and ¹⁵N assignments of the 34 kDa catalytic domain of PTPN5 (STEP)

Biomol NMR Assign. 2014 Apr;8(1):185-8. doi: 10.1007/s12104-013-9480-8. Epub 2013 May 3.

Abstract

PTPN5 is a protein tyrosine phosphatase that plays an integral role in regulating excitatory postsynaptic activity. The sequence-specific backbone assignments of the murine PTPN5 catalytic domain have been determined based on triple-resonance experiments using uniformly [(2)H,(13)C,(15)N]-labeled protein.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Carbon Isotopes
  • Catalytic Domain*
  • Hydrogen
  • Mice
  • Molecular Weight
  • Nitrogen Isotopes
  • Nuclear Magnetic Resonance, Biomolecular*
  • Protein Tyrosine Phosphatases, Non-Receptor / chemistry*

Substances

  • Carbon Isotopes
  • Nitrogen Isotopes
  • Hydrogen
  • Protein Tyrosine Phosphatases, Non-Receptor
  • Ptpn5 protein, mouse