1 Genomic Medicine Institute, Cleveland Clinic, 9500 Euclid Avenue, NE-50, Cleveland, Ohio 44195, USA ; Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA.
2 Genomic Medicine Institute, Cleveland Clinic, 9500 Euclid Avenue, NE-50, Cleveland, Ohio 44195, USA ; Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA ; Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA ; Stanley Shalom Zielony Institute of Nursing Excellence, Cleveland Clinic, Cleveland, Ohio 44195, USA ; Department of Genetics and Genome Sciences, and CASE Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio 44106, USA.