Acrylic kyphoplasty in recent nonosteoporotic fractures of the thoracolumbar junction: a prospective clinical and 3D radiologic study of 54 patients

J Spinal Disord Tech. 2014 Aug;27(6):E226-33. doi: 10.1097/BSD.0b013e31829a3785.

Abstract

Study design: Prospective clinical and radiological study.

Objectives: To evaluate the impact of stand-alone acrylic kyphoplasty in the treatment of recent traumatic fractures of the thoracolumbar spine in young patients.

Summary of background data: The management of fractures of the thoracolumbar spine without neurological deficit remains controversial. For a long time clinicians could only chose between functional treatment, orthopedic treatment, and traditional surgery. The recent advent of minimally invasive surgical techniques is an interesting alternative.

Materials and methods: Fifty-four patients with a mean age of 45.8±18.2 years and who had recently sustained a fracture of the thoracolumbar junction were enrolled into the study. Balloon kyphoplasty was performed using acrylic cement. Radiologic assessments (computed tomography scans) and clinical assessments (including Visual Analog Scale and Oswestry Disability Index scores) were used to determine kyphoplasty success and measure patient recovery over 2 years.

Results: Kyphoplasty reduced mean vertebral kyphosis from 12.8±5.0 degrees at trauma to 8.2±5.1 degrees at 2-year follow-up. Mean vertebral kyphosis was corrected by -5.7±4.7 degrees (P=0.0001) at the point of first verticalization, with no significant change at the 2-year follow-up visit (+1.1±4.3 degrees, P=0.1058). Kyphoplasty significantly augmented the height of the 6 anterior and intermediate segments. Maximum mean augmentation of intermediate vertebral height after 6 months was (11.6%±15.5%, P<0.0001). Patients tolerated the procedure well and 56% of them returned to work 3 months after kyphoplasty.

Conclusion: Kyphoplasty is safe and effective in the correction of nonosteoporotic fractures of the thoracolumbar junction in young patients, and remains stable for at least 2 years postsurgery.

Publication types

  • Clinical Trial

MeSH terms

  • Disability Evaluation
  • Female
  • Humans
  • Kyphoplasty / methods*
  • Lumbar Vertebrae / diagnostic imaging*
  • Lumbar Vertebrae / pathology
  • Lumbar Vertebrae / physiopathology
  • Lumbar Vertebrae / surgery*
  • Male
  • Middle Aged
  • Pain Measurement
  • Polymethyl Methacrylate / therapeutic use*
  • Prospective Studies
  • Spinal Fractures / diagnostic imaging*
  • Spinal Fractures / physiopathology
  • Spinal Fractures / surgery*
  • Thoracic Vertebrae / diagnostic imaging*
  • Thoracic Vertebrae / pathology
  • Thoracic Vertebrae / physiopathology
  • Thoracic Vertebrae / surgery*
  • Tomography, X-Ray Computed
  • Treatment Outcome

Substances

  • Polymethyl Methacrylate