[Maintaining residual renal function in patients on dialysis]

Nephrol Ther. 2013 Nov;9(6):403-7. doi: 10.1016/j.nephro.2013.05.001. Epub 2013 Jun 12.
[Article in French]

Abstract

There are evidences supporting a positive impact of renal residual function (RRF) on survival and quality of life of dialysis patients. Many strategies are available in clinical practices to maintain RRF. Hemodiafiltration seems to be better that conventional hemodialysis and similar to peritoneal dialysis. Arterial hypotension in hemodialysis or dehydration in peritoneal dialysis are deleterious in terms of preservation of RRF. Loop diuretics increase urine volume and natriuresis, not RRF. Radiocontrast and aminoglycosides may be used safely. The benefits of ACE inhibitors and angiotensin II receptor blockers are debated but have positive effect on blood pressure control and cardiac function. Neither biocompatible solutions nor the modality of peritoneal dialysis have demonstrated benefits on RRF.

Keywords: Dialyse péritonéale; Fonction rénale résiduelle; Hemodiafiltration; Hemodialysis; Hémodiafiltration; Hémodialyse; Peritoneal dialysis; Residual renal function.

Publication types

  • English Abstract

MeSH terms

  • Aminoglycosides / therapeutic use
  • Angiotensin Receptor Antagonists / therapeutic use
  • Angiotensin-Converting Enzyme Inhibitors / therapeutic use
  • Contrast Media / adverse effects
  • Diuretics / therapeutic use
  • Humans
  • Kidney / physiopathology*
  • Kidney Failure, Chronic / physiopathology*
  • Kidney Failure, Chronic / therapy*
  • Quality of Life
  • Renal Dialysis*

Substances

  • Aminoglycosides
  • Angiotensin Receptor Antagonists
  • Angiotensin-Converting Enzyme Inhibitors
  • Contrast Media
  • Diuretics