Laryngeal plexiform neurofibroma in a child

Ear Nose Throat J. 2013 Jun;92(6):E31. doi: 10.1177/014556131309200619.

Abstract

Neurofibromatosis (NF) is a genetically inherited, autosomal dominant disease, characterized by multiple cafe au lait spots, cutaneous neurofibromas and "Lisch nodules." Neurofibromatosis can develop from a neural source at any age. However, neurofibroma of the larynx is extremely rare and is usually manifested by obstructive airway symptoms. We encountered a 5-year-old child presenting with stridor and dyspnea, who had a diagnosis of laryngeal plexiform neurofibroma. The purpose of our report is the consideration of laryngeal NF in the differential diagnosis of dyspnea in infants and children.

Publication types

  • Case Reports

MeSH terms

  • Child, Preschool
  • Diagnosis, Differential
  • Dyspnea / etiology*
  • Hemangioma / diagnosis
  • Hoarseness / etiology*
  • Humans
  • Laryngeal Neoplasms / complications*
  • Laryngeal Neoplasms / diagnosis
  • Laryngostenosis / diagnosis
  • Male
  • Neurofibroma, Plexiform / complications*
  • Neurofibroma, Plexiform / diagnosis
  • Neurofibromatosis 1 / complications
  • Neurofibromatosis 1 / diagnosis*
  • Respiratory Sounds / etiology*
  • Vocal Cord Paralysis / etiology