The use of N-ethyl-N-nitrosourea to produce mouse models for human phenylketonuria and hyperphenylalaninemia

MeSH terms

• Amino Acid Metabolism, Inborn Errors / chemically induced
• Amino Acid Metabolism, Inborn Errors / genetics*
• Animals
• Crosses, Genetic
• Disease Models, Animal
• Ethylnitrosourea / toxicity*
• Female
• Humans
• Male
• Mice
• Mice, Mutant Strains
• Mutation
• Phenotype
• Phenylalanine / blood*
• Phenylketonurias / chemically induced
• Phenylketonurias / genetics*