Extended cancer mortality follow-up of a German rubber industry cohort

J Occup Environ Med. 2013 Aug;55(8):966-72. doi: 10.1097/JOM.0b013e31829540f4.

Abstract

Objective: We extended follow-up of a cohort of German rubber industry workers (active or retired in 1981) by 9 years (1992 to 2000) to reassess previously observed cancer mortality risks.

Methods: We calculated standardized mortality ratios and stratified results by work area, duration of employment, and year of hire.

Results: The cohort includes 11,632 men and 1863 women from five tire or general rubber goods producing factories. Among men we observed significantly elevated standardized mortality ratios for cancers of the lung and the pleura in the full cohort and in specific strata. Among women we observed a significantly elevated standardized mortality ratio for cancer of the lung.

Conclusions: We observed excess risk for several cancer sites among men and women. Further cancer risk analysis of workers in the rubber industry should focus on differences in work areas and associated exposures.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Chemical Industry / statistics & numerical data*
  • Female
  • Follow-Up Studies
  • Germany / epidemiology
  • Humans
  • Lung Neoplasms / chemically induced
  • Lung Neoplasms / mortality
  • Male
  • Middle Aged
  • Neoplasms / mortality*
  • Occupational Diseases / chemically induced
  • Occupational Diseases / mortality*
  • Pleural Neoplasms / chemically induced
  • Pleural Neoplasms / mortality
  • Risk Factors
  • Rubber / toxicity*
  • Sex Factors
  • Time Factors
  • Young Adult

Substances

  • Rubber