The elevated number of circulating regulatory T cells in patients with transient hypogammaglobulinemia of infancy is not associated with any abnormalities in the genes encoding the TGF-β receptors

Magdalena Rutkowska; Elżbieta Trzyna; Marzena Lenart; Anna Szaflarska; Anna Pituch-Noworolska; Krzysztof Kobylarz; Maciej Siedlar

doi:10.1016/j.clim.2013.06.008

The elevated number of circulating regulatory T cells in patients with transient hypogammaglobulinemia of infancy is not associated with any abnormalities in the genes encoding the TGF-β receptors

Clin Immunol. 2013 Oct;149(1):83-5. doi: 10.1016/j.clim.2013.06.008. Epub 2013 Jul 13.

Authors

Magdalena Rutkowska¹, Elżbieta Trzyna, Marzena Lenart, Anna Szaflarska, Anna Pituch-Noworolska, Krzysztof Kobylarz, Maciej Siedlar

Affiliation

¹ Department of Clinical Immunology, Polish-American Institute of Pediatrics, Jagiellonian University Medical College, Wielicka 265, Cracow, Poland.

PMID: 23899993
DOI: 10.1016/j.clim.2013.06.008

No abstract available

Keywords: CVID; IL; IgA; Regulatory T cells; SIgAD; T(reg); TGF-β receptors; THI; TβR; common variable immunodeficiency; deficiency; interleukin; regulatory T cells; selective; transforming growth factor β receptor; transient hypogammaglobulinemia of infancy.

Publication types

Letter

MeSH terms

Agammaglobulinemia / genetics*
Agammaglobulinemia / immunology
CD4 Lymphocyte Count
Humans
Infant, Newborn
Molecular Sequence Data
Protein Serine-Threonine Kinases / genetics*
Receptor, Transforming Growth Factor-beta Type I
Receptor, Transforming Growth Factor-beta Type II
Receptors, Transforming Growth Factor beta / genetics*
Sequence Analysis, DNA
T-Lymphocytes, Regulatory / immunology*

Substances

Receptors, Transforming Growth Factor beta
Protein Serine-Threonine Kinases
Receptor, Transforming Growth Factor-beta Type I
Receptor, Transforming Growth Factor-beta Type II