This contribution to an interdisciplinary methodology on Personal Health Monitoring (PHM) aims at developing a psycho-social module for health technology assessment on PHM applications. It covers important aspects that should be taken into account for conducting a health technology assessment from a psycho-social perspective. As it could be used in addition to other tools within the PHM-Ethics approach to health technology assessment it is considered as a module of the interdisciplinary methodology. As a prerequisite, we provide a conceptual framework on psycho-social issues of PHM applications. From that framework we delineate an integrated module for psycho-social health technology assessment for PHM applications, consisting of a map highlighting selective psycho-social issues that may appear when applying a PHM system. This psycho-social tool is at least twofold in its intention as a sole HTA tool on the one hand and as an integral part of the interdisciplinary PHM methodology on the other hand. It provides a quick overview on potential benefits and risks from the user's point of view.