Scalp melanoma in a woman with LEOPARD syndrome: possible implication of PTPN11 signaling in melanoma pathogenesis

J Am Acad Dermatol. 2013 Oct;69(4):e186-7. doi: 10.1016/j.jaad.2013.04.033.

Authors

Yu-Pin Cheng¹, Hsien-Yi Chiu, Tzu-Lin Hsiao, Cheng-Hsiang Hsiao, Chia-Chi Lin, Yi-Hua Liao

Affiliation

¹ Department of Dermatology, National Taiwan University Hospital Hsin-Chu Branch, Hsinchu, Taiwan.

PMID: 24034393
DOI: 10.1016/j.jaad.2013.04.033

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Biopsy, Needle
Female
Follow-Up Studies
Genetic Predisposition to Disease
Germ-Line Mutation
Humans
Immunohistochemistry
LEOPARD Syndrome / complications
LEOPARD Syndrome / genetics*
LEOPARD Syndrome / pathology
Melanoma / complications
Melanoma / genetics*
Melanoma / pathology
Melanoma / surgery
Protein Tyrosine Phosphatase, Non-Receptor Type 11 / genetics*
Risk Assessment
Scalp / pathology*
Signal Transduction / genetics
Skin Neoplasms / complications
Skin Neoplasms / genetics*
Skin Neoplasms / pathology
Skin Neoplasms / surgery
Young Adult

Substances

PTPN11 protein, human
Protein Tyrosine Phosphatase, Non-Receptor Type 11