Influence of the 3K3A-activated protein C variant on the plasma clot lysis activity of t-PA and of t-PA on the variant's anticoagulant activity

J Thromb Haemost. 2013 Nov;11(11):2059-62. doi: 10.1111/jth.12400.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural

MeSH terms

  • Alanine / genetics
  • Anticoagulants / metabolism*
  • Blood Coagulation
  • Dose-Response Relationship, Drug
  • Genetic Variation
  • Humans
  • Ischemia / pathology
  • Ischemia / therapy
  • Mutation
  • Partial Thromboplastin Time
  • Plasminogen / metabolism
  • Protein C / genetics*
  • Protein C / metabolism
  • Recombinant Proteins / metabolism
  • Stroke / pathology
  • Stroke / therapy
  • Thrombin / metabolism
  • Thrombolytic Therapy
  • Time Factors
  • Tissue Plasminogen Activator / metabolism*

Substances

  • Anticoagulants
  • Protein C
  • Recombinant Proteins
  • Plasminogen
  • Thrombin
  • Tissue Plasminogen Activator
  • Alanine