The use of octreotide to manage symptoms of bronchorrhea: a case report

J Pain Symptom Manage. 2014 Apr;47(4):814-8. doi: 10.1016/j.jpainsymman.2013.06.008. Epub 2013 Sep 12.

Abstract

Octreotide, a synthetic analogue of the hormone somatostatin, is primarily used in palliative medicine because of its antisecretory effect and has been shown to be effective in the management of bowel obstruction, nausea, and diarrhea. Octreotide also has been successfully used for the management of bronchorrhea in both inpatient and outpatient settings. We report the case of a 47-year-old female with a history of bronchioloalveolar cell carcinoma whose copious bronchial secretions were controlled with octreotide. Octreotide should be further evaluated as a first-line treatment for bronchorrhea.

Keywords: Bronchorrhea; bronchioloalveolar carcinoma; octreotide.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma, Bronchiolo-Alveolar / complications*
  • Adenocarcinoma, Bronchiolo-Alveolar / physiopathology
  • Adenocarcinoma, Bronchiolo-Alveolar / therapy
  • Antineoplastic Agents, Hormonal / therapeutic use*
  • Bronchi / drug effects
  • Bronchi / metabolism
  • Bronchial Diseases / drug therapy*
  • Bronchial Diseases / etiology
  • Bronchial Diseases / physiopathology
  • Female
  • Humans
  • Lung Neoplasms / complications*
  • Lung Neoplasms / physiopathology
  • Lung Neoplasms / therapy
  • Middle Aged
  • Octreotide / therapeutic use*
  • Palliative Care

Substances

  • Antineoplastic Agents, Hormonal
  • Octreotide