Gold(I)-catalyzed formation of furans from γ-acyloxyalkynyl ketones

Beilstein J Org Chem. 2013 Aug 30:9:1774-80. doi: 10.3762/bjoc.9.206. eCollection 2013.

Abstract

Various γ-acyloxyalkynyl ketones were efficiently converted into highly substituted furans with 2.5 mol % of triflimide (triphenylphosphine)gold(I) as a catalyst in dichloroethane at 70 °C.

Keywords: 1,2-migration; alkynyl ketones; cycloisomerization; furans; gold-catalysis.