Partial sublimation of enantioenriched amino acids at low temperature. Is it coming from the formation of a euatmotic composition of the gaseous phase?

J Org Chem. 2013 Oct 18;78(20):10530-3. doi: 10.1021/jo4017474. Epub 2013 Oct 8.

Abstract

The partial sublimation of enantioenriched amino acids was performed slowly at low temperature with the aim to determine the rules of sublimation of these compounds. Although the formation of a euatmotic composition of the gaseous phase starting from DL + L mixtures of Leu, Pro, and Phe can be deduced from the enantiomeric excess of sublimates, the behavior of the kinetic conglomerate explains the results for D + L mixtures of Ala, Leu, Val, and Pro. Consequently, the enantiomeric excess of the partial sublimate is dependent not only on the studied compound but also on the composition of the starting mixture.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Amino Acids / chemistry*
  • Kinetics
  • Peptide Fragments / chemistry*
  • Stereoisomerism
  • Temperature

Substances

  • Amino Acids
  • Peptide Fragments