Probing the mobility of ibuprofen confined in MCM-41 materials using MAS-PFG NMR and hyperpolarised-(129)Xe NMR spectroscopy

Flavien Guenneau; Kuldeep Panesar; Andrei Nossov; Marie-Anne Springuel-Huet; Thierry Azaïs; Florence Babonneau; Corine Tourné-Péteilh; Jean-Marie Devoisselle; Antoine Gédéon

doi:10.1039/c3cp52695j

Probing the mobility of ibuprofen confined in MCM-41 materials using MAS-PFG NMR and hyperpolarised-(129)Xe NMR spectroscopy

Phys Chem Chem Phys. 2013 Nov 21;15(43):18805-8. doi: 10.1039/c3cp52695j.

Authors

Flavien Guenneau¹, Kuldeep Panesar, Andrei Nossov, Marie-Anne Springuel-Huet, Thierry Azaïs, Florence Babonneau, Corine Tourné-Péteilh, Jean-Marie Devoisselle, Antoine Gédéon

Affiliation

¹ UPMC Univ Paris 06, Collège de France and CNRS, UMR 7574, Laboratoire de Chimie de la Matière Condensée de Paris, case 196, 4 place Jussieu, 75252 Paris Cedex 05, France. flavien.guenneau@upmc.fr.

PMID: 24100415
DOI: 10.1039/c3cp52695j

Abstract

The continuous-flow hyperpolarised (HP)-(129)Xe NMR and magic angle spinning-pulsed field gradient (MAS-PFG) NMR techniques have been used for the first time to study the distribution and the dynamics of ibuprofen encapsulated in MCM-41 with two different pore diameters.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Diffusion
Ibuprofen / chemistry*
Magnetic Resonance Spectroscopy
Porosity
Silicon Dioxide / chemistry*
Xenon Isotopes / chemistry

Substances

MCM-41
Xenon Isotopes
Silicon Dioxide
Ibuprofen