Abstract
Oral alitretinoin (9-cis retinoic acid) is an endogenous retinoid related to vitamin A. Studies have shown that oral alitretinoin is effective and well-tolerated in the treatment of severe chronic hand eczema, so that it is approved for this indication. This review summarizes new studies and clinical experience on the off-label use of alitretinoin.
MeSH terms
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Alitretinoin
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Chronic Disease
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Dermatologic Agents / adverse effects
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Dermatologic Agents / therapeutic use
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Drug-Related Side Effects and Adverse Reactions / etiology*
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Drug-Related Side Effects and Adverse Reactions / prevention & control
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Eczema / drug therapy*
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Evidence-Based Medicine*
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Hand Dermatoses / drug therapy*
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Humans
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Off-Label Use*
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Treatment Outcome
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Tretinoin / adverse effects*
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Tretinoin / therapeutic use*
Substances
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Dermatologic Agents
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Alitretinoin
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Tretinoin