Case of mumps orchitis after vaccination

Int J Urol. 2014 Apr;21(4):426-8. doi: 10.1111/iju.12305. Epub 2013 Oct 24.

Abstract

We present a case of mumps orchitis after vaccination. A 35-year-old man visited the emergency unit of our hospital for fever and right testicular pain on 7 January 2012. Two weeks before the visit, he underwent vaccination for mumps. After 7 days of hospitalization, the patient recovered from fever and testicular pain. Scrotal magnetic resonance imaging suggested right orchitis, and an increased level of serum mumps immunoglobulin M and immunoglobulin G indicated an initial infection of mumps virus. The peak value of immunoglobulin G showed 106 enzyme immunoassay unit 5 weeks after vaccination, which was 10-fold higher than the ordinary rise of a vaccinated individual. This fact leads to two possibilities. One is this happened as an adverse event of vaccination, and the other is that he actually had a wild-type infection at the same time as vaccination. There are some reports regarding adverse events of mumps vaccine; however, they might include wild-type infection.

Keywords: mumps; post-vaccine orchitis; vaccination.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Mumps / etiology*
  • Mumps / pathology
  • Mumps Vaccine / adverse effects*
  • Orchitis / etiology*
  • Orchitis / pathology

Substances

  • Mumps Vaccine