Androgen insensitivity syndrome diagnosed in an elderly patient during a strangulated inguinal hernia repair

Abstract

Introduction: A strangulated inguinal hernia is a common indication for emergency surgery. In comparison, complete testicular feminization is a rare genetic disease that can present with an inguinal hernia because of ectopically positioned testicles.

Presentation of case: A 70-year-old female was admitted to the emergency service complaining of a painful swelling in the right inguinal region for 1 day. The physical examination indicated a strangulated inguinal hernia and surgery was performed. On exploring the inguinal region, a strangulated indirect inguinal hernia and hard 2×3-cm mass were detected. The histopathological examination of the excised mass showed testicular tissue, and complete testicular feminization (CTF) was diagnosed after further examinations.

Discussion: Androgen insensitivity syndrome (AIS), the most frequent cause of male pseudohermaphroditism. The diagnosis of patients with AIS is usually made at the beginning of the second decade when a healthy person with a female phenotype complains of no menarche. Making a first diagnosis after the 5th decade is extremely rare.

Conclusion: While AIS can be diagnosed in early adulthood, cases might not bediagnosed until the patient is of advanced age.

Keywords: Androgen insensitivity; Elderly; Testicular feminization.